This study is investigating treatment of post-traumatic headache after mild traumatic brain injury (concussion). Participants will need to have experienced a headache after their recent concussion. There are several parts to this study, which include in person study visits, daily headache questions, and weekly telephone calls.
After completing a baseline interview, participants will be randomly put into one of two groups. Group 1 will begin study medication right away, and Group 2 will wait 30 days to possibly begin medication. The study medication is called, Amitriptyline, and is a FDA approved medication for treating symptoms of depression and for the prevention of migraine headaches.
- Be within 12 weeks of mild TBI (also known as concussion).
- Have experienced a headache since their injury.
- Be between the ages of 18 and 65.
- Not be currently pregnant or planning to become pregnant during study participation.
- Be able to come in person to Harborview Medical Center or the University of Washington.
- Have access to a telephone for weekly telephone calls.
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